The macrophage-activating tetrapeptide tuftsin induces nitric oxide synthesis and stimulates murine macrophages to kill Leishmania parasites in vitro.

The macrophage-activating tetrapeptide tuftsin was able to activate, in a dose-dependent manner, murine macrophages to express nitric oxide (NO) synthase and to produce NO. Tuftsin required lipopolysaccharides for the optimal induction of NO production and synergized with gamma interferon in the ind...

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Detalhes bibliográficos
Main Authors: Cillari, E, Arcoleo, F, Dieli, M, D'Agostino, R, Gromo, G, Leoni, F, Milano, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC186561/
https://ncbi.nlm.nih.gov/pubmed/8188392
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