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Down-regulation of iron regulatory protein 1 gene expression by nitric oxide

Iron regulatory protein 1 (IRP1) is an RNA binding protein that posttranscriptionally modulates the expression of mRNAs coding for proteins involved in iron metabolism. It has long been held that its RNA binding activity is regulated posttranslationally by the insertion/extrusion of a 4Fe-4S cluster...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Oliveira, Leonor, Drapier, Jean-Claude
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2000
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18655/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10823926/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.120571797
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