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Down-regulation of iron regulatory protein 1 gene expression by nitric oxide

Iron regulatory protein 1 (IRP1) is an RNA binding protein that posttranscriptionally modulates the expression of mRNAs coding for proteins involved in iron metabolism. It has long been held that its RNA binding activity is regulated posttranslationally by the insertion/extrusion of a 4Fe-4S cluster...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Oliveira, Leonor, Drapier, Jean-Claude
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2000
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18655/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10823926/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.120571797
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