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A genome-scale computational study of the interplay between transcriptional regulation and metabolism
This paper presents a new method, steady-state regulatory flux balance analysis (SR-FBA), for predicting gene expression and metabolic fluxes in a large-scale integrated metabolic–regulatory model. Using SR-FBA to study the metabolism of Escherichia coli, we quantify the extent to which the differen...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1865583/ https://ncbi.nlm.nih.gov/pubmed/17437026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100141 |
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