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Regional Variation in the Density of Essential Genes in Mice

In most species, and particularly in vertebrates, the percentage of genes absolutely required for survival, the essential genes, has not been estimated. To obtain this estimation, we used the mouse as an experimental model to carry out high-efficiency N-ethyl-N-nitrosourea (ENU) mutagenesis screens...

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Autors principals: Hentges, Kathryn E, Pollock, David D, Liu, Bin, Justice, Monica J
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865562/
https://ncbi.nlm.nih.gov/pubmed/17480122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030072
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