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Regional Variation in the Density of Essential Genes in Mice

In most species, and particularly in vertebrates, the percentage of genes absolutely required for survival, the essential genes, has not been estimated. To obtain this estimation, we used the mouse as an experimental model to carry out high-efficiency N-ethyl-N-nitrosourea (ENU) mutagenesis screens...

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Autori principali: Hentges, Kathryn E, Pollock, David D, Liu, Bin, Justice, Monica J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865562/
https://ncbi.nlm.nih.gov/pubmed/17480122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030072
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