Inhibition of phospholipase D blocks activation of fibrinogen-adherent neutrophils by tumor necrosis factor.
Tumor necrosis factor stimulates fibrinogen-adherent neutrophils to produce a dramatic oxidative burst; the resulting superoxide and other products may contribute to tissue damage in severe infection. Inhibitors of the phospholipase D pathway blocked this activation without affecting cell adherence...
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| Publicado no: | Infect Immun |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186555/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8188387/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.6.2622-2624.1994 |
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