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Excision of Sleeping Beauty transposons: parameters and applications to gene therapy

A major problem in gene therapy is the determination of the rates at which gene transfer has occurred. Our work has focused on applications of the Sleeping Beauty (SB) transposon system as a non-viral vector for gene therapy. Excision of a transposon from a donor molecule and its integration into a...

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Bibliographic Details
Main Authors: Liu, Geyi, Aronovich, Elena L., Cui, Zongbin, Whitley, Chester B., Hackett, Perry B.
Format: Artigo
Language:Inglês
Published: 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865527/
https://ncbi.nlm.nih.gov/pubmed/15133768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.486
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