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Crystallographic snapshot of a productive glycosylasparaginase-substrate complex
Glycosylasparaginase (GA) plays an important role in asparagine-linked glycoprotein degradation. A deficiency in the activity of human GA leads to a lysosomal storage disease named aspartylglycosaminuria. GA belongs to a superfamily of N-terminal nucleophile hydrolases that autoproteolytically gener...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1865511/ https://ncbi.nlm.nih.gov/pubmed/17157318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.09.051 |
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