Chargement en cours...
The T99K variant of glycosylasparaginase shows a new structural mechanism of the genetic disease aspartylglucosaminuria
Aspartylglucosaminuria (AGU) is an inherited disease caused by mutations in a lysosomal amidase called aspartylglucosaminidase (AGA) or glycosylasparaginase (GA). This disorder results in an accumulation of glycoasparagines in the lysosomes of virtually all cell types, with severe clinical symptoms...
Enregistré dans:
| Publié dans: | Protein Sci |
|---|---|
| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley & Sons, Inc.
2019
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6511735/ https://ncbi.nlm.nih.gov/pubmed/30901125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3607 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|