Antibodies to presenilin proteins detect neurofibrillary tangles in Alzheimer's disease.

Mutations in the presenilin (PS)-1 and PS-2 genes have been shown to be linked with the development of Alzheimer's disease (AD). We examined Alzheimer's brain tissue by immunohistochemistry using a set of antibodies raised to sequences shared between PS-1 and PS-2 proteins. These antibodie...

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Autores principales: Murphy, G. M., Forno, L. S., Ellis, W. G., Nochlin, D., Levy-Lahad, E., Poorkaj, P., Bird, T. D., Jiang, Z., Cordell, B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1996
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865361/
https://ncbi.nlm.nih.gov/pubmed/8952521
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