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Monoclonal antibodies to Alzheimer neurofibrillary tangles. 1. Identification of polypeptides.

Ten monoclonal antibodies to Alzheimer neurofibrillary tangles (ANTs) were produced by immunizing mice with a brain homogenate from senile dementia of the Alzheimer type (SDAT). In methanol-fixed isolated neuronal perikarya, six of these antibodies reacted with nearly every ANT, three recognized 70-...

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Main Authors: Yen, S. H., Crowe, A., Dickson, D. W.
Formato: Artigo
Idioma:Inglês
Publicado: 1985
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887824/
https://ncbi.nlm.nih.gov/pubmed/2411142
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