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Consensus-interferon and platelet-derived growth factor adversely regulate proliferation and migration of Kaposi's sarcoma cells by control of c-myc expression.

Platelet-derived growth factor-B (PDGF-B) is a potent paracrine-acting mitogen in Kaposi's sarcoma (KS) lesions. Interferon-alpha is widely used for clinical treatment of KS. Here we show that platelet-derived growth factor-B activates proliferation and migration of cultivated AIDS-KS spindle c...

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Detalhes bibliográficos
Main Authors: Köster, R., Blatt, L. M., Streubert, M., Zietz, C., Hermeking, H., Brysch, W., Stürzl, M.
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865356/
https://ncbi.nlm.nih.gov/pubmed/8952524
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