Induction of lymphocyte proliferation and severe gastrointestinal disease in macaques by a nef gene variant SIVmac239.

The molecularly cloned virus known as SIVmac239/YEnef causes extensive lymphocyte activation in unstimulated peripheral mononuclear cell cultures and induces an acute disease syndrome in macaque monkeys. Here we describe the histopathological and immunophenotypic changes and viral localization in pe...

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Hlavní autoři: Sasseville, V. G., Du, Z., Chalifoux, L. V., Pauley, D. R., Young, H. L., Sehgal, P. K., Desrosiers, R. C., Lackner, A. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1996
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865222/
https://ncbi.nlm.nih.gov/pubmed/8686740
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