Induction of lymphocyte proliferation and severe gastrointestinal disease in macaques by a nef gene variant SIVmac239.

The molecularly cloned virus known as SIVmac239/YEnef causes extensive lymphocyte activation in unstimulated peripheral mononuclear cell cultures and induces an acute disease syndrome in macaque monkeys. Here we describe the histopathological and immunophenotypic changes and viral localization in pe...

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Main Authors: Sasseville, V. G., Du, Z., Chalifoux, L. V., Pauley, D. R., Young, H. L., Sehgal, P. K., Desrosiers, R. C., Lackner, A. A.
Formato: Artigo
Idioma:Inglês
Publicado: 1996
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865222/
https://ncbi.nlm.nih.gov/pubmed/8686740
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