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Novel DNA probes with low background and high hybridization-triggered fluorescence
Novel fluorogenic DNA probes are described. The probes (called Pleiades) have a minor groove binder (MGB) and a fluorophore at the 5′-end and a non-fluorescent quencher at the 3′-end of the DNA sequence. This configuration provides surprisingly low background and high hybridization-triggered fluores...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1865069/ https://ncbi.nlm.nih.gov/pubmed/17259212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1136 |
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