Interaction between trichosanthin, a ribosome-inactivating protein, and the ribosomal stalk protein P2 by chemical shift perturbation and mutagenesis analyses

Trichosanthin (TCS) is a type I ribosome-inactivating protein that inactivates ribosome by enzymatically depurinating the A(4324) at the α-sarcin/ricin loop of 28S rRNA. We have shown in this and previous studies that TCS interacts with human acidic ribosomal proteins P0, P1 and P2, which constitute...

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Detalhes bibliográficos
Main Authors: Chan, Denise S.B., Chu, Lai-On, Lee, Ka-Ming, Too, Priscilla H.M., Ma, Kit-Wan, Sze, Kong-Hung, Zhu, Guang, Shaw, Pang-Chui, Wong, Kam-Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865052/
https://ncbi.nlm.nih.gov/pubmed/17308345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm065
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