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Meiotic resumption in response to luteinizing hormone is independent of a G(i) family G protein or calcium in the mouse oocyte.

The signaling pathway by which luteinizing hormone (LH) acts on the somatic cells of vertebrate ovarian follicles to stimulate meiotic resumption in the oocyte requires a decrease in cAMP in the oocyte, but how cAMP is decreased is unknown. Activation of G(i)-family G proteins can lower cAMP by inhi...

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Detalhes bibliográficos
Main Authors: Mehlmann, Lisa M., Kalinowski, Rebecca R., Ross, Lavinia F., Parlow, Albert F., Hewlett, Erik L., Jaffe, Laurinda A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1864934/
https://ncbi.nlm.nih.gov/pubmed/16949564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2006.07.039
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