Deletion of the phosphoinositide 3-kinase p110γ gene attenuates murine atherosclerosis

Inflammatory cell activation by chemokines requires intracellular signaling through phosphoinositide 3-kinase (PI3-kinase) and the PI3-kinase-dependent protein serine/threonine kinase Akt. Atherosclerosis is a chronic inflammatory process driven by oxidatively modified (atherogenic) lipoproteins, ch...

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Bibliographische Detailangaben
Hauptverfasser: Chang, James D., Sukhova, Galina K., Libby, Peter, Schvartz, Eugenia, Lichtenstein, Alice H., Field, Seth J., Kennedy, Caitlin, Madhavarapu, Swetha, Luo, Ji, Wu, Dianqing, Cantley, Lewis C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2007
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1864909/
https://ncbi.nlm.nih.gov/pubmed/17483449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702663104
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