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Unusual Thermal Stability of RNA/[R(P)-PS]-DNA/RNA Triplexes Containing a Homopurine DNA Strand

Homopurine deoxyribonucleoside phosphorothioates, as short as hexanucleotides and possessing all internucleotide linkages of R(P) configuration, form a triple helix with two RNA or 2′-OMe-RNA strands, with Watson-Crick and Hoogsteen complementarity. Melting temperature and fluorescence quenching exp...

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Detalhes bibliográficos
Main Authors: Guga, Piotr, Boczkowska, Małgorzata, Janicka, Magdalena, Maciaszek, Anna, Kuberski, Sławomir, Stec, Wojciech J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1864848/
https://ncbi.nlm.nih.gov/pubmed/17218459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.099283
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