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Partial destruction of Borrelia burgdorferi within ticks that engorged on OspE- or OspF-immunized mice.

We determined whether Borrelia burgdorferi outer surface proteins (Osps) E and F could elicit immune responses useful for a Lyme disease vaccine. Thirty days after challenge with B. burgdorferi, mice produced antibodies to OspE but not OspF, whereas antibodies to OspF were present in sera of mice ob...

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Bibliographic Details
Main Authors: Nguyen, T P, Lam, T T, Barthold, S W, Telford, S R, Flavell, R A, Fikrig, E
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC186469/
https://ncbi.nlm.nih.gov/pubmed/8168973
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