The Drosophila heterochromatic gene encoding poly(ADP-ribose) polymerase (PARP) is required to modulate chromatin structure during development

Poly(ADP-ribose) polymerase (PARP) is a major NAD-dependent modifying enzyme that mediates important steps in DNA repair, transcription, and apoptosis, but its role during development is poorly understood. We found that a single Drosophila Parp gene spans more than 150 kb of transposon-rich centrome...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Tulin, Alexei, Stewart, Dianne, Spradling, Allan C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 2002
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186441/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12183365/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1003902
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