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The Drosophila heterochromatic gene encoding poly(ADP-ribose) polymerase (PARP) is required to modulate chromatin structure during development
Poly(ADP-ribose) polymerase (PARP) is a major NAD-dependent modifying enzyme that mediates important steps in DNA repair, transcription, and apoptosis, but its role during development is poorly understood. We found that a single Drosophila Parp gene spans more than 150 kb of transposon-rich centrome...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2002
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC186441/ https://ncbi.nlm.nih.gov/pubmed/12183365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1003902 |
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