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The Drosophila heterochromatic gene encoding poly(ADP-ribose) polymerase (PARP) is required to modulate chromatin structure during development

Poly(ADP-ribose) polymerase (PARP) is a major NAD-dependent modifying enzyme that mediates important steps in DNA repair, transcription, and apoptosis, but its role during development is poorly understood. We found that a single Drosophila Parp gene spans more than 150 kb of transposon-rich centrome...

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Detalhes bibliográficos
Main Authors: Tulin, Alexei, Stewart, Dianne, Spradling, Allan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC186441/
https://ncbi.nlm.nih.gov/pubmed/12183365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1003902
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