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Shh establishes an Nkx3.2/Sox9 autoregulatory loop that is maintained by BMP signals to induce somitic chondrogenesis

Prior work has established that transient Shh signals from the notochord and floor plate confer a competence in somitic tissue for subsequent BMP signals to induce chondrogenesis. We have therefore proposed that Shh induces a factor(s) that renders somitic cells competent to chondrify in response to...

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Autores principales: Zeng, Li, Kempf, Hervé, Murtaugh, L. Charles, Sato, Mie Elissa, Lassar, Andrew B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC186419/
https://ncbi.nlm.nih.gov/pubmed/12154128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1008002
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