Evidence that the A2 fragment of Shiga-like toxin type I is required for holotoxin integrity.
Escherichia coli Shiga-like toxin type I (SLT-I) is a potent cytotoxin consisting of an enzymatically active A subunit and a pentameric B subunit that mediates toxin binding to susceptible eukaryotic cells. Evidence that the carboxy-terminal 38 amino acids of the A subunit are involved in holotoxin...
Αποθηκεύτηκε σε:
| Εκδόθηκε σε: | Infect Immun |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Microbiology (ASM)
1994
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186405/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8168939/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.5.1768-1775.1994 |
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