Evidence that the A2 fragment of Shiga-like toxin type I is required for holotoxin integrity.

Escherichia coli Shiga-like toxin type I (SLT-I) is a potent cytotoxin consisting of an enzymatically active A subunit and a pentameric B subunit that mediates toxin binding to susceptible eukaryotic cells. Evidence that the carboxy-terminal 38 amino acids of the A subunit are involved in holotoxin...

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Pubblicato in:	Infect Immun
Autori principali:	Austin, P R, Jablonski, P E, Bohach, G A, Dunker, A K, Hovde, C J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186405/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8168939/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.5.1768-1775.1994
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