Investigation of routes and funnels in protein folding by free energy functional methods
We use a free energy functional theory to elucidate general properties of heterogeneously ordering, fast folding proteins, and we test our conclusions with lattice simulations. We find that both structural and energetic heterogeneity can lower the free energy barrier to folding. Correlating stronger...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2000
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18640/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10841554/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.12.6509 |
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