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Free hydroxyl groups are not required for endotoxic activity of lipid A.

Previous studies demonstrated that lipid A from Salmonella abortusequi loses its B-cell mitogenicity for murine spleen cells as a result of the introduction of succinyl residues on hydroxyl groups and that the inactivated lipid A specifically antagonizes the mitogenicity of endotoxin. Hypothesizing...

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Detalhes bibliográficos
Publicado no:Infect Immun
Autor principal: Tanamoto, K
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186388/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8168931/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.5.1705-1709.1994
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