Free hydroxyl groups are not required for endotoxic activity of lipid A.
Previous studies demonstrated that lipid A from Salmonella abortusequi loses its B-cell mitogenicity for murine spleen cells as a result of the introduction of succinyl residues on hydroxyl groups and that the inactivated lipid A specifically antagonizes the mitogenicity of endotoxin. Hypothesizing...
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| Veröffentlicht in: | Infect Immun |
|---|---|
| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
1994
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186388/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8168931/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.5.1705-1709.1994 |
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