Transcriptional repression of the gluconeogenic gene PEPCK by the orphan nuclear receptor SHP through inhibitory interaction with C/EBPα

SHP (short heterodimer partner) is an orphan nuclear receptor that plays an important role in regulating glucose and lipid metabolism. A variety of transcription factors are known to regulate transcription of the PEPCK (phosphoenolpyruvate carboxykinase) gene, which encodes a rate-determining enzyme...

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Hlavní autoři: Park, Min Jung, Kong, Hee Jeong, Kim, Hye Young, Kim, Hyeong Hoe, Kim, Joon Hong, Cheong, Jae Hun
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2007
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1863575/
https://ncbi.nlm.nih.gov/pubmed/17094771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061549
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