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Cryptochromes impair phosphorylation of transcriptional activators in the clock: a general mechanism for circadian repression

CLOCK and BMAL1 [brain and muscle ARNT (arylhydrocarbon receptor nuclear translocator)-like protein 1] are central components of the molecular clock in mammals and belong to the bHLH (basic helix–loop–helix)/PAS [PER (Period)/ARNT/SIM (single-minded)] family. Features of their dimerization have neve...

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Detalhes bibliográficos
Main Authors: Dardente, Hugues, Fortier, Erin E., Martineau, Vincent, Cermakian, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1863574/
https://ncbi.nlm.nih.gov/pubmed/17115977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060827
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