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Fatal gastrointestinal obstruction and hypertension in mice lacking nitric oxide-sensitive guanylyl cyclase

The signaling molecule nitric oxide (NO), first described as endothelium-derived relaxing factor (EDRF), acts as physiological activator of NO-sensitive guanylyl cyclase (NO-GC) in the cardiovascular, gastrointestinal, and nervous systems. Besides NO-GC, other NO targets have been proposed; however,...

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Detalhes bibliográficos
Main Authors: Friebe, Andreas, Mergia, Evanthia, Dangel, Oliver, Lange, Alexander, Koesling, Doris
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1863512/
https://ncbi.nlm.nih.gov/pubmed/17452643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609778104
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