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Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expression
IL-17 is the founding member of a novel family of proinflammatory cytokines that defines a new class of CD4(+) effector T cells, termed “Th17.” Mounting evidence suggests that IL-17 and Th17 cells cause pathology in autoimmunity, but little is known about mechanisms of IL-17RA signaling. IL-17 throu...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1863505/ https://ncbi.nlm.nih.gov/pubmed/17456598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611589104 |
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