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Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E

The coordinated action of cell cycle progression and cell growth (an increase in cell size and cell mass) is critical for sustained cellular proliferation, yet the biochemical signals that control cell growth are poorly defined, particularly in mammalian systems. We find that cell growth and cell cy...

Cur síos iomlán

Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:Genes Dev
Príomhchruthaitheoirí: Fingar, Diane C., Salama, Sofie, Tsou, Christina, Harlow, Ed, Blenis, John
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Cold Spring Harbor Laboratory Press 2002
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186342/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12080086/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.995802
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