Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E

The coordinated action of cell cycle progression and cell growth (an increase in cell size and cell mass) is critical for sustained cellular proliferation, yet the biochemical signals that control cell growth are poorly defined, particularly in mammalian systems. We find that cell growth and cell cy...

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Podrobná bibliografie

Vydáno v:	Genes Dev
Hlavní autoři:	Fingar, Diane C., Salama, Sofie, Tsou, Christina, Harlow, Ed, Blenis, John
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Cold Spring Harbor Laboratory Press 2002
Témata:	Research Paper
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186342/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12080086/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.995802
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