Inhibitory effect of deferoxamine or macrophage activation on transformation of Paracoccidioides brasiliensis conidia ingested by macrophages: reversal by holotransferrin.

Conidia of P. brasiliensis ingested by murine macrophages at 37 degrees C showed enhanced transformation to yeast cells and further intracellular growth compared with conidia in culture medium alone. Treatment of macrophages with the iron chelator deferoxamine inhibited the intracellular conidium-to...

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Bibliografische gegevens
Hoofdauteurs: Cano, L E, Gomez, B, Brummer, E, Restrepo, A, Stevens, D A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1994
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC186311/
https://ncbi.nlm.nih.gov/pubmed/8132359
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