Novel path to apoptosis: small transmembrane pores created by staphylococcal alpha-toxin in T lymphocytes evoke internucleosomal DNA degradation.

Peripheral-blood human T lymphocytes were treated with Staphylococcus aureus alpha-toxin. Membrane permeabilization was assessed by measuring efflux of K+ and Rb+ and influx of Na+, Ca2+, and propidium iodide. Cellular ATP and [3H]thymidine incorporation following lectin stimulation were measured as...

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Pubblicato in:	Infect Immun
Autori principali:	Jonas, D, Walev, I, Berger, T, Liebetrau, M, Palmer, M, Bhakdi, S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186275/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8132337/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.4.1304-1312.1994
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