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Nf2 gene inactivation in arachnoidal cells is rate-limiting for meningioma development in the mouse
Biallelic NF2 gene inactivation is common in sporadic and in neurofibromatosis type 2 (NF2)-related meningiomas. We show that, beginning at four months of age, thirty percent of mice with arachnoidal cell Cre-mediated excision of Nf2 exon 2 developed a range of meningioma subtypes histologically sim...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC186259/ https://ncbi.nlm.nih.gov/pubmed/12000789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.226302 |
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