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Functional assays for BRCA1 and BRCA2

Genetic testing for the two major breast cancer susceptibility genes has now been available for several years with more than 70,000 people tested in the USA alone. While the current genetic testing identifies many sequence alterations there are problems with both sensitivity and specificity of the a...

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Bibliographic Details
Main Authors: Carvalho, Marcelo A., Couch, Fergus J., Monteiro, Alvaro N. A.
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1862449/
https://ncbi.nlm.nih.gov/pubmed/16978908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2006.08.002
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