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Effects of mutation and growth rates on patterns of microsatellite instability.

The detection of somatic microsatellite (MS) alterations in tumors is often interpreted as a sign of underlying genomic instability. However, it is unclear why the proportions of altered MS loci vary between different mutator phenotype tumors. We present a simple mathematical analysis that can accou...

詳細記述

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書誌詳細
主要な著者: Li, Z. H., Aaltonen, L. A., Shu, Q., Srivastava, S., Grizzle, W. E., Shibata, D.
フォーマット: Artigo
言語:Inglês
出版事項: 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1861626/
https://ncbi.nlm.nih.gov/pubmed/8669462
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