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Direct stimulation of limbal microvessel endothelial cell proliferation and capillary formation in vitro by a corneal-derived eicosanoid.

12(R)-Hydroxyeicosatrienoic acid (12(R)-HETrE), a corneal epithelial derived inflammatory eicosanoid, elicits blood vessel growth into the avascular cornea in the classical corneal micropocket bioassay. Using an in vivo stimulated angiogenesis assay and 12(R)-HETrE as the angiogenic stimulus, we iso...

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Bibliographic Details
Main Authors: Stoltz, R. A., Conners, M. S., Gerritsen, M. E., Abraham, N. G., Laniado-Schwartzman, M.
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1861607/
https://ncbi.nlm.nih.gov/pubmed/8546200
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