Transfection of the human heme oxygenase gene into rabbit coronary microvessel endothelial cells: protective effect against heme and hemoglobin toxicity.

Heme oxygenase (HO) is a stress protein and has been suggested to participate in defense mechanisms against agents that may induce oxidative injury such as metals, endotoxin, heme/hemoglobin, and various cytokines. Overexpression of HO in cells might therefore protect against oxidative stress produc...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Abraham, N G, Lavrovsky, Y, Schwartzman, M L, Stoltz, R A, Levere, R D, Gerritsen, M E, Shibahara, S, Kappas, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41416/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7624322/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.15.6798
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