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Depression of liver metabolism and induction of cytokine release by diphtheria and tetanus toxoids and pertussis vaccines: role of Bordetella pertussis cells in toxicity.

A 24-h pretreatment of mice with diphtheria and tetanus toxoids and whole-cell pertussis vaccines depressed liver cytochrome P-450 and therefore prolonged hexobarbital-induced sleeping time in mice. The depression of liver drug metabolism by a cellular vaccine containing a mutated pertussis toxin wa...

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Библиографические подробности
Опубликовано в::Infect Immun
Главные авторы: Fantuzzi, G, Sironi, M, Delgado, R, Cantoni, L, Rizzardini, M, Carelli, M, Marsili, I, Ghiara, P, Ghezzi, P
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1994
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186063/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8262641/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.1.29-32.1994
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