Depression of liver metabolism and induction of cytokine release by diphtheria and tetanus toxoids and pertussis vaccines: role of Bordetella pertussis cells in toxicity.

A 24-h pretreatment of mice with diphtheria and tetanus toxoids and whole-cell pertussis vaccines depressed liver cytochrome P-450 and therefore prolonged hexobarbital-induced sleeping time in mice. The depression of liver drug metabolism by a cellular vaccine containing a mutated pertussis toxin wa...

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Auteurs principaux: Fantuzzi, G, Sironi, M, Delgado, R, Cantoni, L, Rizzardini, M, Carelli, M, Marsili, I, Ghiara, P, Ghezzi, P
Format: Artigo
Langue:Inglês
Publié: 1994
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC186063/
https://ncbi.nlm.nih.gov/pubmed/8262641
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