Topoisomerase IIα in Wilms' tumour: gene alterations and immunoexpression

BACKGROUND: Topoisomerase IIα (topoIIα) is an essential enzyme gene in regulating DNA structure and cell proliferation and is encoded by the TOP2A . Using cDNA microarray analysis, TOP2A has been reported to be one of the top genes overexpressed in Wilms' tumour. AIM: To evaluate the role of To...

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Detalhes bibliográficos
Main Authors: Tretiakova, M, Turkyilmaz, M, Grushko, T, Kocherginsky, M, Rubin, C, Teh, B, Yang, X J
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1860548/
https://ncbi.nlm.nih.gov/pubmed/16556665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2005.031963
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