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Isolated haploinsufficiency of exon 1 of the SHOX gene in a patient with idiopathic short stature

This paper reports the case of a 16‐year‐old woman with idiopathic short stature (ISS) who was detected to be haploinsufficient in only exon 1 of the short stature homeobox‐containing (SHOX) gene by RQ‐PCR and had two copies of the other six exons intact. The translation of the SHOX protein and of t...

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Hlavní autoři: Tan, Y‐M, Loke, K‐Y
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Group 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1860432/
https://ncbi.nlm.nih.gov/pubmed/16803952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2005.028894
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