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An update on molecular genetics of gastrointestinal stromal tumours

Gastrointestinal stromal tumours (GISTs) are the most common primary mesenchymal tumours of the gastrointestinal tract. Most of them show activating mutations of the genes coding for KIT or platelet‐derived growth factor receptor α (PDGFRα), two receptor tyrosine kinases (RTKs). The RTK inhibitor Im...

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Detalles Bibliográficos
Main Authors: Tornillo, L, Terracciano, L M
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Group 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1860404/
https://ncbi.nlm.nih.gov/pubmed/16731599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2005.031112
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