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An update on molecular genetics of gastrointestinal stromal tumours
Gastrointestinal stromal tumours (GISTs) are the most common primary mesenchymal tumours of the gastrointestinal tract. Most of them show activating mutations of the genes coding for KIT or platelet‐derived growth factor receptor α (PDGFRα), two receptor tyrosine kinases (RTKs). The RTK inhibitor Im...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMJ Group
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1860404/ https://ncbi.nlm.nih.gov/pubmed/16731599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2005.031112 |
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