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Immune tolerance to autoantibody-derived peptides delays development of autoimmunity in murine lupus.

Mechanisms that initiate and maintain autoantibody (autoAb) production in individuals with autoimmune diseases like SLE are poorly understood. Inadequate suppression of autoreactive T cells and/or unusual activation of T and B cells may underlie the persistence of pathogenic autoAbs in lupus. Here,...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Singh, R R, Ebling, F M, Sercarz, E E, Hahn, B H
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1995
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186011/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8675671/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118371
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