Immune tolerance to autoantibody-derived peptides delays development of autoimmunity in murine lupus.

Mechanisms that initiate and maintain autoantibody (autoAb) production in individuals with autoimmune diseases like SLE are poorly understood. Inadequate suppression of autoreactive T cells and/or unusual activation of T and B cells may underlie the persistence of pathogenic autoAbs in lupus. Here,...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Singh, R R, Ebling, F M, Sercarz, E E, Hahn, B H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186011/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8675671/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118371
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