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Targeted tumor killing via an intracellular antibody against erbB-2.

Specific killing of erbB-2-overexpressing tumor cells can be achieved using expression of an intracellular antibody directed against the erbB-2 oncoprotein. We have developed a strategy using a recombinant adenovirus encoding an anti-erbB-2 single chain antibody to achieve targeted tumor cell killin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Deshane, J, Siegal, G P, Alvarez, R D, Wang, M H, Feng, M, Cabrera, G, Liu, T, Kay, M, Curiel, D T
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC186010/
https://ncbi.nlm.nih.gov/pubmed/8675670
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